الرئيسية
الأبحاث العلمية
التدريس
التدرج الوظيفى
السيرة الذاتية
البحث الأكاديمى
إتصل بنا
الموقع الجديد
المجالات البحثية
الكيمياء الطبية
الابحاث العلمية
1 -
Design and Synthesis of Novel Thienopyrimidine Derivatives with Potential Biological Activity (2024).
2 -
Design, Synthesis and Evaluation of Novel Inhibitors of E2 Ubiquitin Conjugating Enzyme as Potential Breast Cancer Therapeutics (2024).
3 -
Synthesis and biological screening of new quinazolin-4(3H)-one and benzotriazepine derivatives (2024).
4 -
Synthesis of New 2,3-dihydroquinazolinones and their Tricyclic Derivatives for Biological Evaluation (2024).
5 -
Synthesis of 1, 2, 4‐triazole and 1, 3, 4‐oxadiazole derivatives as inhibitors for STAT3 enzymes of breast cancer (2023).
6 -
Magic shotgun approach to anti-inflammatory pharmacotherapy: Synthesis of novel thienopyrimidine monomers/heterodimer as dual COX-2 and 15-LOX inhibitors endowed with potent antioxidant activity (2023).
7 -
Synthesis of new multitarget-directed ligands containing thienopyrimidine nucleus for inhibition of 15-lipoxygenase, cyclooxygenases, and pro-inflammatory cytokines (2023).
8 -
Triple targeting of mutant EGFRL858R/T790M, COX-2, and 15-LOX: design and synthesis of novel quinazolinone tethered phenyl urea derivatives for anti-inflammatory and anticancer evaluation (2023).
9 -
Phenylalanyl tRNA synthetase (PheRS) substrate mimics: design, synthesis, molecular dynamics and antimicrobial evaluation (2022).
10 -
Design, computational studies, synthesis and in vitro antimicrobial evaluation of benzimidazole based thio-oxadiazole and thio-thiadiazole analogues (2021).
11 -
Quinazoline‐tethered hydrazone: A versatile scaffold toward dual anti‐TB and EGFR inhibition activities in NSCLC (2021).
12 -
Quinazolinone dimers as a potential new class of safer Kv1 inhibitors: Overcoming hERG, sodium and calcium channel affinities (2021).
13 -
Design and synthesis of novel quinazolinones conjugated ibuprofen, indole acetamide, or thioacetohydrazide as selective COX-2 inhibitors: anti-inflammatory, analgesic and anticancer activities (2021).
14 -
Novel 1,2,4-triazine-quinoline hybrids: The privileged scaffolds as potent multi-target inhibitors of LPS-induced inflammatory response via dual COX-2 and 15-LOX inhibition (2021).
15 -
Synthesis, In vivo and In silico Evaluation of Novel 2,3-Dihydroquinazolin-4(1H)-one Derivatives as Potential Anticonvulsant Agents (2019).
16 -
1,4-Dihydroquinazolin-3(2H)-yl benzamide derivatives as anti-inflammatory and analgesic agents with an improved gastric profile: Design, synthesis, COX-1/2 inhibitory activity and molecular docking study (2018).
17 -
Design, synthesis and biological evaluation of novel quinazoline-2,4- diones conjugated with different amino acids as potential chitin synthase inhibitors (2018).
18 -
RAD6 promotes DNA repair and stem cell signaling in ovarian cancer and is a promising therapeutic target to prevent and treat acquired chemoresistance (2017).
19 -
Synthesis, Anticonvulsant Activity, and SAR Study of Novel 4-Quinazolinone Derivatives (2017).
20 -
Synthesis, Anticonvulsant Activity, and SAR Study of Novel 4-Quinazolinone Derivatives (2017).
21 -
Preclinical evaluation of Rad6 inhibition to overcome platinum resistance in ovarian cancer (2016).
22 -
Gold nanoparticle conjugated Rad6 inhibitor induces cell death in triple negative breast cancer cells by inducing mitochondrial dysfunction and PARP-1 hyperactivation: Synthesis and characterization (2016).
23 -
Synthesis and in vitro anticancer evaluation of some 4,6-diamino-1,3,5-triazine-2-carbohydrazides as Rad6 ubiquitin conjugating enzyme inhibitors (2016).
24 -
Design, synthesis and in vitro anticancer evaluation of 4,6-diamino-1,3,5-triazine-2-carbohydrazides and -carboxamides (2013).
25 -
Novel Inhibitors of Rad6 Ubiquitin Conjugating Enzyme: Design, Synthesis, Identification, and Functional Characterization (2013).
26 -
Synthesis of new benzotriazepin-5(2H)-one derivatives of expected antipsychotic activity (2013).
27 -
Synthesis of New 2,3-Dihydroquinazolin-4(1H)-one Derivatives for Analgesic and Anti-inflammatory Evaluation (2010).
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دخول
2014 all rights reserved.
Zagazig University
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